Located on the border between California and Nevada, in the Great Basin and the Mojave Desert, southeast of the Sierra Nevada mountains, Death Valley constitutes much of Death Valley National Park and is the principal feature of the Mojave and Colorado Deserts Biosphere Reserve. It is located mostly in Inyo County, California. It runs from north to south between the Amargosa Range on the east and the Panamint Range on the west; the Sylvania Mountains and the Owlshead Mountains form its northern and southern boundaries, respectively. It has an area of about 3,000 sq mi (7,800 km2). Death Valley shares many characteristics with other places around the world that lie below sea level.

The depth and shape of Death Valley influence its summer temperatures. The valley is a long, narrow basin 282 feet (86 m) below sea level, yet is walled by high, steep mountain ranges. The clear, dry air and sparse plant cover allow sunlight to heat the desert surface. Heat radiates back from the rocks and soil, then becomes trapped in the valley's depths. Summer nights provide little relief as overnight lows may only dip into the 86°F to 95°F (30°C to 35°C) range. Heated air rises, yet is trapped by the high valley walls, is cooled and recycled back down to the valley floor. These pockets of descending air are only slightly cooler than the surrounding hot air. As they descend, they are compressed and heated even more by the low elevation air pressure. These moving masses of super heated air blow through the valley creating extreme high temperatures.